APC, APC regulator of WNT signaling pathway, 324

N. diseases: 95; N. variants: 596
Disease: Colorectal Neoplasms ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 Biomarker group CTD_human 4-Hydroxy-2(E)-nonenal metabolism differs in Apc(+/+) cells and in Apc(Min/+) cells: it may explain colon cancer promotion by heme iron. 21967605 2011
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 Biomarker group CTD_human Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations. 21531761 2011
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 Biomarker group CTD_human Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression. 21291235 2011
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 Biomarker group CTD_human The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients. 19309276 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 Biomarker group CTD_human Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia. 18716850 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 Biomarker group CTD_human Dietary folate and APC mutations in sporadic colorectal cancer. 17116713 2006
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 Biomarker group CTD_human Proteomic analysis of intestinal epithelial cells expressing stabilized beta-catenin. 12907644 2003
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.900 GeneticVariation group UNIPROT