APC, APC regulator of WNT signaling pathway, 324

N. diseases: 95; N. variants: 596
Disease: Intestinal Neoplasms ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021841
Disease: Intestinal Neoplasms
Intestinal Neoplasms 		0.400 Biomarker group CTD_human Gene Expression Profile of Colon Mucosa after Cytotoxic Insult in wt and Apc-Mutated Pirc Rats: Possible Relation to Resistance to Apoptosis during Carcinogenesis. 27840820 2016
CUI: C0021841
Disease: Intestinal Neoplasms
Intestinal Neoplasms 		0.400 Biomarker group CTD_human Sulindac, 3,3'-diindolylmethane and curcumin reduce carcinogenesis in the Pirc rat, an Apc-driven model of colon carcinogenesis. 26335331 2015
CUI: C0021841
Disease: Intestinal Neoplasms
Intestinal Neoplasms 		0.400 Biomarker group CTD_human Crypt stem cells as the cells-of-origin of intestinal cancer. 19092804 2009
CUI: C0021841
Disease: Intestinal Neoplasms
Intestinal Neoplasms 		0.400 Biomarker group CTD_human Role of nucleotide excision repair deficiency in intestinal tumorigenesis in multiple intestinal neoplasia (Min) mice. 16962818 2006
CUI: C0021841
Disease: Intestinal Neoplasms
Intestinal Neoplasms 		0.400 Biomarker group CTD_human Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice. 14706516 2004
CUI: C0021841
Disease: Intestinal Neoplasms
Intestinal Neoplasms 		0.400 Biomarker group CTD_human Short-term carcinogenicity testing of a potent murine intestinal mutagen, 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), in Apc1638N transgenic mice. 9111214 1997