APC, APC regulator of WNT signaling pathway, 324

N. diseases: 703; N. variants: 681
Disease: Rectal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0034885
Disease: Rectal Neoplasms
Rectal Neoplasms 		0.320 GeneticVariation group LHGDN Meat and fish consumption, APC gene mutations and hMLH1 expression in colon and rectal cancer: a prospective cohort study (The Netherlands). 16184469 2005
CUI: C0034885
Disease: Rectal Neoplasms
Rectal Neoplasms 		0.320 Biomarker group CTD_human Attenuated familial adenomatous polyposis associated with advanced rectal cancer in a 16-year-old boy: report of a case. 11766074 2001
CUI: C0034885
Disease: Rectal Neoplasms
Rectal Neoplasms 		0.320 GeneticVariation group BEFREE These results suggest that tumor or tumor suppressor genes, other than the APC gene, may be responsible for extramammary Paget's disease and SCC and that LOH involving APC may have some relevance to the formation and progression of eccrine tumors as in rectal tumors. 10674823 2000
CUI: C0034885
Disease: Rectal Neoplasms
Rectal Neoplasms 		0.320 Biomarker group CTD_human Adenomatous polyposis coli and a cytogenetic deletion of chromosome 5 resulting from a maternal intrachromosomal insertion. 8071957 1994