|
Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
PPD skin test was positive but tuberculosis antibody test and T-SPOT were negative.
|
30813161 |
2019 |
|
Hawkinsinuria
|
0.730 |
GeneticVariation
|
disease |
BEFREE |
A heterozygous missense mutation predicting an Ala to Thr change at codon 33 (A33T) was found in the same HPD gene in the two patients with hawkinsinuria.
|
11073718 |
2000 |
|
Hawkinsinuria
|
0.730 |
GeneticVariation
|
disease |
ORPHANET |
A heterozygous missense mutation predicting an Ala to Thr change at codon 33 (A33T) was found in the same HPD gene in the two patients with hawkinsinuria.
|
11073718 |
2000 |
|
Tyrosinemia, Type III
|
0.940 |
GeneticVariation
|
disease |
BEFREE |
A homozygous missense mutation predicting an Ala to Val change at codon 268 (A268V) in the HPD gene was found in the patient with tyrosinemia type III.
|
11073718 |
2000 |
|
Tyrosinemia, Type III
|
0.940 |
Biomarker
|
disease |
CLINGEN |
A homozygous missense mutation predicting an Ala to Val change at codon 268 (A268V) in the HPD gene was found in the patient with tyrosinemia type III.
|
11073718 |
2000 |
|
Tyrosinemia, Type III
|
0.940 |
GeneticVariation
|
disease |
UNIPROT |
A homozygous missense mutation predicting an Ala to Val change at codon 268 (A268V) in the HPD gene was found in the patient with tyrosinemia type III.
|
11073718 |
2000 |
|
Tyrosinemia, Type III
|
0.940 |
Biomarker
|
disease |
MGD |
A murine model for type III tyrosinemia: lack of immunologically detectable 4-hydroxyphenylpyruvic acid dioxygenase enzyme protein in a novel mouse strain with hypertyrosinemia.
|
2014797 |
1991 |
|
Tyrosinemia, Type III
|
0.940 |
Biomarker
|
disease |
CLINGEN |
A nonsense mutation in the 4-hydroxyphenylpyruvic acid dioxygenase gene (Hpd) causes skipping of the constitutive exon and hypertyrosinemia in mouse strain III.
|
7774914 |
1995 |
|
Hepatitis, Toxic
|
0.300 |
Biomarker
|
disease |
CTD_human |
A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.
|
22872058 |
2012 |
|
Hepatitis, Drug-Induced
|
0.300 |
Biomarker
|
disease |
CTD_human |
A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.
|
22872058 |
2012 |
|
Drug-Induced Acute Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.
|
22872058 |
2012 |
|
Chemical and Drug Induced Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.
|
22872058 |
2012 |
|
Chemically-Induced Liver Toxicity
|
0.300 |
Biomarker
|
disease |
CTD_human |
A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.
|
22872058 |
2012 |
|
Seed corn
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
A population of Amaranthus tuberculatus (var. rudis) was confirmed resistant to 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibitor herbicides (mesotrione, tembotrione, and topramezone) in a seed corn/soybean rotation in Nebraska.
|
28799707 |
2018 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
All the results suggest that 4-XL-PPD exhibited remarkable anticancer activity base on inducing apoptosis via generating reactive oxygen species and inhibiting migratory and invasive, which support development of 4-XL-PPD as a potential agent for cancer therapy.
|
31382131 |
2019 |
|
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
All the results suggest that 4-XL-PPD exhibited remarkable anticancer activity base on inducing apoptosis via generating reactive oxygen species and inhibiting migratory and invasive, which support development of 4-XL-PPD as a potential agent for cancer therapy.
|
31382131 |
2019 |
|
Tyrosinemia, Type III
|
0.940 |
Biomarker
|
disease |
CLINGEN |
Assay, properties and tissue distribution of p-hydroxyphenylpyruvate hydroxylase.
|
4627454 |
1972 |
|
Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Carriage of the Gc2 allele was associated with increased PPD of tuberculin-stimulated IFN-gamma release in Gujarati Asian TB contacts (p = 0.02).
|
19797128 |
2010 |
|
Progressive pseudorheumatoid dysplasia
|
0.030 |
Biomarker
|
disease |
BEFREE |
Cell-mediated immunity was characterized in whole blood samples as the differential release of interferon-gamma in response to bovine purified protein derivative (PPDb) and avian PPD (PPDa) as well as the release of this cytokine in response to the <i>M. bovis</i> proteins 6 kDa early secretory antigenic target (ESAT-6)/10 kDa culture filtrate protein (CFP-10).
|
29312328 |
2017 |
|
Periodontal inflammation
|
0.010 |
Biomarker
|
disease |
BEFREE |
Clinical dental examinations comprised caries experience (DMF/T-Index), signs of periodontal inflammation (probing pocket depth, PPD; community periodontal index of treatment needs; CPITN) at six index teeth and oral hygiene (OH).
|
28578462 |
2018 |
|
Venezuelan equine encephalomyelitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Coalescent analysis performed on RNV sequences suggested a common ancestor of 58.3 years (with a 95% highest posterior density [HPD] interval of 16.4-345.7) prior to 1991 and inferred a substitution rate of 9.8×10(-5)substitutions/site/year, slightly lower than other enzootic VEE viruses.
|
24833218 |
2014 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Combining 25-OCH3-PPD with conventional chemotherapeutic agents or with radiation led to potent antitumour effects; tumour regression was almost complete following administration of 25-OCH3-PPD and either taxotere or gemcitabine.
|
18253123 |
2008 |
|
Tuberculosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Comparative sensitivity of the test with tuberculosis recombinant allergen, containing ESAT6-CFP10 protein, and Mantoux test with 2 TU PPD-L in newly diagnosed tuberculosis children and adolescents in Moscow.
|
30576322 |
2018 |
|
Anemia of chronic disease
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Conclusion: The high level of skin sensitization due to nickel, PPD, and gold in patients with ACD emphasizes the need for measures to decrease exposure to these sensitizing agents.
|
28889150 |
2017 |
|
Avellino corneal dystrophy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Conclusion: The high level of skin sensitization due to nickel, PPD, and gold in patients with ACD emphasizes the need for measures to decrease exposure to these sensitizing agents.
|
28889150 |
2017 |