HRAS, HRas proto-oncogene, GTPase, 3265

N. diseases: 698; N. variants: 29
Disease: Actinic keratosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022602
Disease: Actinic keratosis
Actinic keratosis 		0.030 GeneticVariation disease BEFREE Moreover, we suggest that the HRAS codon 12 mutation is not a very common event in AK or NMSC. 19849697 2010
CUI: C0022602
Disease: Actinic keratosis
Actinic keratosis 		0.030 GeneticVariation disease LHGDN Low prevalence of p53, p16(INK4a) and Ha-ras tumour-specific mutations in low-graded actinic keratosis. 17488404 2007
CUI: C0022602
Disease: Actinic keratosis
Actinic keratosis 		0.030 GeneticVariation disease BEFREE The evaluation of a large number of AK specimens in this study have found a low gene mutation rate in low-graded AK lesions. p53 mutations rather than p16(INK4a) and/or Ha-ras mutations may be an early event in the development of AK to cutaneous SCC. 17488404 2007
CUI: C0022602
Disease: Actinic keratosis
Actinic keratosis 		0.030 GeneticVariation disease BEFREE Only one solar keratosis (4%) showed a point mutation in the Ha-ras gene but not in the p53 gene. 9778107 1998