|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
Gene expression analysis in the lung of the rasH2 transgenic mouse at week 4 prior to induction of malignant tumor formation by urethane and N-methylolacrylamide.
|
26558449 |
2015 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress.
|
24898257 |
2014 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.
|
18758463 |
2008 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
BEFREE |
Rapid induction of skin tumors in human but not mouse c-Ha-ras proto-oncogene transgenic mice by chemical carcinogenesis.
|
16805855 |
2006 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model.
|
15958052 |
2005 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
BEFREE |
Finally, the E2F1 transgene is found to cooperate with a v-Ha-ras transgene to induce skin tumors in double transgenic animals.
|
9546428 |
1998 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
In skin tumors, AZT exposure did not increase the number of Ha-ras codon 61 mutations, and no Ki-ras mutations were observed.
|
9766437 |
1998 |
|
Skin Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
These results demonstrate that TGF alpha, through EGFR overstimulation, can act synergistically with TPA to induce the formation, growth, and development of DMBA-initiated skin tumors containing classic Ha-ras gene mutations but not p53 gene inactivation.
|
9115586 |
1997 |
|
Skin Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
ACNU-induced skin tumors harbored mutations in the c-Ha-ras gene in both groups of mice.
|
9269990 |
1997 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
Characterization of skin tumor promotion by mirex: structure-activity relationships, sexual dimorphism and presence of Ha-ras mutation.
|
8508502 |
1993 |
|
Skin Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
Chemically induced skin carcinogenesis in a transgenic mouse line (TG.AC) carrying a v-Ha-ras gene.
|
8330346 |
1993 |
|
Skin Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
In vitro DNA amplification followed by oligonucleotide mismatch hybridization was used to study the frequency of HRAS mutations in the benign self-regressing skin tumors keratoacanthomas and in squamous cell carcinomas.
|
2668964 |
1989 |
|
Skin Neoplasms
|
0.360 |
GeneticVariation
|
group |
BEFREE |
DNAs were isolated from 35 pairs of skin tumors (25 BCCs and 10 SCCs) and matching normal skin from the same patients and analyzed for c-Ha-ras gene polymorphism by Southern blot hybridization.
|
2690853 |
1989 |