HRAS, HRas proto-oncogene, GTPase, 3265

N. diseases: 698; N. variants: 29
Disease: Adenoma of large intestine ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		0.060 GeneticVariation disease BEFREE We hypothesized that aneuploidy among human sporadic colorectal adenomas and KRAS2 and APC mutations were not independent. 15623940 2004
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		0.060 GeneticVariation disease BEFREE Kirsten ras (Ki-ras) gene mutations occur early in the progression of colorectal adenoma to carcinoma. 9586664 1998
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		0.060 GeneticVariation disease BEFREE The aim of this study was to investigate the prognostic value of K-RAS-2 gene mutations found in initial colorectal adenomas for predicting the risk of metachronous adenomas. 9361177 1997
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		0.060 GeneticVariation disease BEFREE The present series of sporadic colorectal adenomas indicates that codon 12 G-C and G-T K-ras-2 transversion mutations and DNA aneuploidy are correlated. 7698570 1995
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		0.060 GeneticVariation disease BEFREE The ELISA is a feasible and valid approach for identifying p21ras mutations in human colorectal adenomas and carcinomas. 8625092 1995
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		0.060 GeneticVariation disease BEFREE Higher frequency of point mutations in the c-K-ras 2 gene in human colorectal adenomas with severe atypia than in carcinomas. 1708754 1991