Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.030 Biomarker disease BEFREE Thus, the present study was designed to define a critical pathway by which Ape1 mediates neurotoxicity in a model of PD. 27893608 2017
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.030 GeneticVariation disease BEFREE We investigated the contributions of functional SNPs in 2 BER genes (APEX1 and OGG1) and mitochondrial dysfunction- or oxidative stress-related pesticide exposure, including paraquat, to PD risk. 28460087 2017
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.030 GeneticVariation disease BEFREE In the light of these findings, we investigated whether DNA repair gene polymorphisms (XRCC1 Arg399Gln, XRCC3 Thr241Met XPD Lys751Gln, XPG Asp1104His, APE1 Asp148Glu, and HOGG1 Ser326Cys) account for an increased risk of Parkinson's disease (PD). 22224629 2012