HES1, hes family bHLH transcription factor 1, 3280

N. diseases: 243; N. variants: 0
Disease: Anaplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002793
Disease: Anaplasia
Anaplasia 		0.010 Biomarker disease BEFREE In hypoxic neuroblastoma cells, proneuronal lineage specifying transcription factors, and their dimerization partner E2-2, were downregulated, whereas their inhibitors Id2 and HES-1 were induced, providing a molecular mechanism for the hypoxia-provoked dedifferentiation of neuroblastoma cells. 15093745 2004