HES1, hes family bHLH transcription factor 1, 3280

N. diseases: 243; N. variants: 0
Disease: Blast Phase ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005699
Disease: Blast Phase
Blast Phase 		0.030 Biomarker disease BEFREE Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells. 24825862 2014
CUI: C0005699
Disease: Blast Phase
Blast Phase 		0.030 AlteredExpression disease BEFREE Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis. 24486648 2014
CUI: C0005699
Disease: Blast Phase
Blast Phase 		0.030 Biomarker disease BEFREE Similarly, Fyn deficiency failed to impact the development of myeloid CML-BC induced by Bcr-Abl and Hes1. 22189847 2012