HES1, hes family bHLH transcription factor 1, 3280

N. diseases: 243; N. variants: 0
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.030 Biomarker disease BEFREE HES1 activation suppresses proliferation of leukemia cells in acute myeloid leukemia. 26092281 2015
CUI: C0023418
Disease: leukemia
leukemia 		0.030 AlteredExpression disease BEFREE Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis. 24486648 2014
CUI: C0023418
Disease: leukemia
leukemia 		0.030 GeneticVariation disease BEFREE Transforming polypeptides also demonstrated moderate to strong activation of the Su(H)/CBF1-sensitive HES-1 promoter, while polypeptides with weak or absent activity on this promoter failed to cause leukemia. 11003647 2000