Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003467
Disease: Anxiety
Anxiety
0.040 GeneticVariation disease BEFREE Feto-placental HSD2 deletion resulted in a reduced birthweight and the development of anxiety- and depression-like behaviours in adult mice. 30884491 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.040 AlteredExpression disease BEFREE These findings suggest that maternal depression and anxiety may impact on fetal programming by down-regulating HSD11B2, and antidepressant treatment alone is unlikely to protect against this effect. 26593902 2015
CUI: C0003467
Disease: Anxiety
Anxiety
0.040 Biomarker disease BEFREE On the other hand, infants whose mothers reported anxiety during pregnancy and showed greater methylation of placental 11β-HSD-2 CpG4 were more hypotonic compared with infants of mothers who did not report anxiety during pregnancy. 24135662 2013
CUI: C0003467
Disease: Anxiety
Anxiety
0.040 AlteredExpression disease BEFREE Prenatal Trait anxiety was negatively correlated with placental 11β-HSD2 mRNA expression (r=-0.40, p<0.01, n=56). 22001010 2012