HSF1, heat shock transcription factor 1, 3297

N. diseases: 185; N. variants: 4
Disease: Cervix carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.020 Biomarker disease BEFREE Heat shock factor 1 (HSF1) is a transcription factor essential for tumorigenesis, and targeting HSF1 may be effective in combined therapeutics for cervical cancer. 31054961 2019
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.020 Biomarker disease BEFREE These findings indicate that disruption of HSF1-induced cytoprotection during hyperthermochemotherapy may represent a powerful strategy to selectively amplify the damage in cancer cells and identify HSF1 as a promising therapeutic target in cervical carcinoma. 16885369 2006