HSF1, heat shock transcription factor 1, 3297

N. diseases: 185; N. variants: 4
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 Biomarker group BEFREE SIGNIFICANCE: These findings identify heat shock transcription factor 1 as a new substrate for PIM2 kinase and establish its role in breast tumor progression. 31409638 2019
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 Biomarker group BEFREE <i>In vitro</i> transfection of PLK1 and HSF1 siRNA into PKL1- and HSF1-positive human breast tumor MDA-MB-231 and human cervical carcinoma HeLa cells inhibited cell growth via suppression of PLK1 and HSF1 mRNA expression, respectively. 29067111 2017
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 GeneticVariation group LHGDN Blocking HSF1 by dominant-negative mutant to sensitize tumor cells to hyperthermia. 11820785 2002