HSF4, heat shock transcription factor 4, 3299

N. diseases: 31; N. variants: 10
Disease: AIDS related complex ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001857
Disease: AIDS related complex
AIDS related complex 		0.020 GeneticVariation disease BEFREE Our previous study identified five new heat shock factor 4 (HSF4) mutations in 150 age-related cataract (ARC) patients which indicated that HSF4 mutations may be associated with this disease. 25088997 2014
CUI: C0001857
Disease: AIDS related complex
AIDS related complex 		0.020 Biomarker disease BEFREE The combination WRN and HSF4 CNVs markedly increased the risk of ARC; the OR was increased from 2.63 by HSF4 alone to 6.80 by combined WRN and HSF4 CNVs. 23329665 2013