HSF4, heat shock transcription factor 4, 3299

N. diseases: 31; N. variants: 10
Disease: Age-related cataract ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.060 GeneticVariation disease BEFREE Our previous study identified five new heat shock factor 4 (HSF4) mutations in 150 age-related cataract (ARC) patients which indicated that HSF4 mutations may be associated with this disease. 25088997 2014
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.060 GeneticVariation disease BEFREE HSF4 mutation p.Arg116His found in age-related cataracts and in normal populations produces childhood lamellar cataract in transgenic mice. 24975927 2014
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.060 GeneticVariation disease BEFREE HSF4 mutations lead to both congenital and age-related cataract. 23507146 2013
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.060 GeneticVariation disease BEFREE Mutations in the HSF4 gene lead to congenital and senile cataract. 22587838 2012
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.060 GeneticVariation disease BEFREE Mutations of the human HSF4 gene have been implicated in congenital and age-related cataracts. 20670914 2010
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.060 Biomarker disease BEFREE In this study, we explore the role of HSF4 in the development of age-related cataract. 18941546 2008