BIRC3, baculoviral IAP repeat containing 3, 330

N. diseases: 209; N. variants: 3
Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.320 AlteredExpression disease BEFREE In MM, cIAP2 is part of the gene signature of aberrant NF-κB signaling and is heterogeneously expressed amongst MM patients. 26036313 2015
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.320 Biomarker disease BEFREE These data define a fundamental role for cIAP1/cIAP2 in regulating B-cell survival and responsiveness, show this requires direct binding to TRAF2, and suggest how mutations of TRAF2, TRAF3, and cIAP1/cIAP2 contribute to B-lineage malignancies, such as multiple myeloma. 21300983 2011
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.320 CausalMutation disease CGI