Disease: Alzheimer's Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.230 Biomarker disease BEFREE These compounds further improved neurite outgrowth, reduced AChE activity and upregulated the molecular chaperone heat shock protein family B [small] member 1 (HSP27), whereas knockdown of HSP27 counteracted the compounds' neuroprotective effects on the Tet-On Aβ-GFP SH-SY5Y AD neuronal model. 30707915 2019
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.230 Biomarker disease RGD Intraneuronal accumulation of misfolded tau protein induces overexpression of Hsp27 in activated astrocytes. 25772164 2015
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.230 AlteredExpression disease BEFREE These results suggest that overexpression of Hsp27 protein might ameliorate certain symptoms of AD. 23605646 2013
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.230 Biomarker disease BEFREE HspB1, an sHsp commonly associated with senile plaques in Alzheimer's disease (AD), prevents the toxic effects of Aβ aggregates in vitro. 21670152 2011