BIRC5, baculoviral IAP repeat containing 5, 332

N. diseases: 199; N. variants: 11
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.050 Biomarker disease BEFREE Notably, cell-cycle aberrations and copy number gains in BIRC2, BIRC3 and BIRC5 were significantly associated with poor melanoma-specific survival in the 66 patients with melanoma and especially in the 45 patients with AM. 31408190 2019
CUI: C0025202
Disease: melanoma
melanoma 		0.050 AlteredExpression disease LHGDN IGF1 promotes resistance to apoptosis in melanoma cells through an increased expression of BCL2, BCL-X(L), and survivin. 18079751 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.050 Biomarker disease LHGDN Nuclear survivin is associated with disease recurrence and poor survival in patients with cutaneous malignant melanoma. 17543072 2007
CUI: C0025202
Disease: melanoma
melanoma 		0.050 AlteredExpression disease LHGDN Survivin protein in UVB induced apoptosis of melanoma cells and in melanoma progression. 15870931 2005
CUI: C0025202
Disease: melanoma
melanoma 		0.050 AlteredExpression disease LHGDN Survivin expression by metastatic melanoma predicts poor disease outcome in patients receiving adjuvant polyvalent vaccine. 15986442 2005