Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE However, the status of HSP60 in diabetes and obesity is unclear. 29467719 2018
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE Heat shock protein 60 (Hsp60) is an adipokine, and its serum concentrations are higher in patients with obesity compared to lean patients. 29024428 2017
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE We investigated whether feeding a high-fat diet to C57BL/6J mice would cause autoimmunity to HSP60 and whether immunomodulation with peptides from HSP60 would reverse the resulting obesity or metabolic dysfunction. 27899808 2017
CUI: C0028754
Disease: Obesity
Obesity
0.040 Biomarker disease BEFREE HSP60 reduction in obese, diabetic mice was due to a lack of proper leptin signaling and was restored by leptin treatment. 24084737 2013