|
Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We performed array-CGH to look for copy number variants between five pairs of monozygotic twins discordant for bipolar disorder or schizophrenia.
|
23507357 |
2013 |
|
Schizophrenia
|
0.320 |
Biomarker
|
disease |
BEFREE |
We suggest that CGH microarray should be performed in cases with intractable epilepsy or schizophrenia, with or without mental retardation.
|
21145272 |
2011 |
|
Neuroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In high-risk patients, CGH+SNP microarray analysis of primary neuroblastoma identifies SRCIN1 as frequently altered by hemizygous deletion, copy-neutral loss of heterozygosity, or disruption.
|
31285546 |
2020 |
|
Central neuroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In high-risk patients, CGH+SNP microarray analysis of primary neuroblastoma identifies SRCIN1 as frequently altered by hemizygous deletion, copy-neutral loss of heterozygosity, or disruption.
|
31285546 |
2020 |
|
Childhood Neuroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In high-risk patients, CGH+SNP microarray analysis of primary neuroblastoma identifies SRCIN1 as frequently altered by hemizygous deletion, copy-neutral loss of heterozygosity, or disruption.
|
31285546 |
2020 |
|
Congenital Abnormality
|
0.100 |
Biomarker
|
group |
BEFREE |
The most frequent a-CGH abnormalities were detected in cases of congenital heart diseases (CDHs), multiple malformations and central nervous system (CNS) malformations.
|
30638470 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Only 10 CGH array assays were contributive and concluded in complex chromosomal patterns as hallmarks of malignancy in 5 melanomas, single isolated imbalances in 3 nevi, and no chromosomal gain or loss in 2 nevi.
|
28362709 |
2019 |
|
Congenital chromosomal disease
|
0.100 |
Biomarker
|
group |
BEFREE |
Therefore, a Gaussian pdf is not adequate to approximate the noise in array CGH data and hence introduces wrong detections of chromosomal aberrations and leads misunderstanding on disease pathogenesis.
|
28692986 |
2019 |
|
Congenital chromosomal disease
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Patients with atypical values of HCG and/or PAPP-A are at higher risk of chromosomal abnormality and vascular complications of pregnancy.
|
31779618 |
2019 |
|
Congenital chromosomal disease
|
0.100 |
Biomarker
|
group |
BEFREE |
SNP array, array CGH and FISH were useful for the complete characterization of the chromosomal aberrations, for the detection of microdeletions in patients with normal karyotype but with strong clinical suspicious of chromosomal alteration, and for a better establishment of genotype-phenotype correlation.
|
31730496 |
2019 |
|
Developmental delay (disorder)
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Array-CGH increased the diagnostic rate of developmental delay or intellectual disability in Taiwan.
|
30581099 |
2019 |
|
Developmental delay (disorder)
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Using array CGH, 262 patients with deletions and 215 with duplications were identified and tested for their association with four phenotypes (developmental delay, dysmorphic features, autism group of disorders, and epilepsy/seizures).
|
30542208 |
2019 |
|
Global developmental delay
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Using array CGH, 262 patients with deletions and 215 with duplications were identified and tested for their association with four phenotypes (developmental delay, dysmorphic features, autism group of disorders, and epilepsy/seizures).
|
30542208 |
2019 |
|
Global developmental delay
|
0.100 |
Biomarker
|
disease |
BEFREE |
Array-CGH increased the diagnostic rate of developmental delay or intellectual disability in Taiwan.
|
30581099 |
2019 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Only 10 CGH array assays were contributive and concluded in complex chromosomal patterns as hallmarks of malignancy in 5 melanomas, single isolated imbalances in 3 nevi, and no chromosomal gain or loss in 2 nevi.
|
28362709 |
2019 |
|
Intellectual Disability
|
0.100 |
Biomarker
|
group |
BEFREE |
Array-CGH increased the diagnostic rate of developmental delay or intellectual disability in Taiwan.
|
30581099 |
2019 |
|
Congenital Abnormality
|
0.100 |
Biomarker
|
group |
BEFREE |
Factors associated with pathological results in array-CGH were a family history of GDD/ID (OR = 12.1), congenital malformations (OR = 5.33), having more than 3 facial dysmorphic features (OR = 20.9), and hypotonia (OR = 3.25).
|
27157524 |
2018 |
|
Congenital Abnormality
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Prematurity, ventricular septal defect and dysmorphisms are independent predictors of pathogenic copy number variants: a retrospective study on array-CGH results and phenotypical features of 293 children with neurodevelopmental disorders and/or multiple congenital anomalies.
|
29523172 |
2018 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The patient's thyroid function normalised with treatment of the cancer as the beta HCG levels declined.
|
29884717 |
2018 |
|
Congenital chromosomal disease
|
0.100 |
Biomarker
|
group |
BEFREE |
Genetic screening for chromosomopathy is performed in the first trimester of pregnancy by determining fetal nuchal translucency (NT), and the pregnancy associated plasma protein-A (PAPP-A) and free human chorionic gonadotropin (free-beta HCG) biomarkers in maternal serum.
|
30581343 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Of these 19 patients, 17 did not have elevated CSF HCG-β levels or express HCG-β in the tumor tissue.
|
28819802 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Circulating tumor markers (β-subunit of human chorionic gonadotropin (β-HCG), alpha-Fetoprotein (AFP), and Lactate Dehydrogenase (LDH)) are frequently used for monitoring disease recurrence in TGCT patients, though they lack diagnostic sensitivity and specificity.
|
30321995 |
2018 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The aim of this study was to define the pattern of numerical chromosomal alterations in tumor samples taken from 20 patients with pcAECyTCL at the time of diagnosis by means of array-comparative genomic hybridization (a-CGH). a-CGH detected numerous genomic aberrations in all the patients and, putting these together as a whole, they affected all the chromosomes.
|
30307677 |
2018 |
|
Dysmorphic features
|
0.100 |
Biomarker
|
disease |
BEFREE |
Factors associated with pathological results in array-CGH were a family history of GDD/ID (OR = 12.1), congenital malformations (OR = 5.33), having more than 3 facial dysmorphic features (OR = 20.9), and hypotonia (OR = 3.25).
|
27157524 |
2018 |
|
Primary malignant neoplasm
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The patient's thyroid function normalised with treatment of the cancer as the beta HCG levels declined.
|
29884717 |
2018 |