|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
HDL-C (for PVWMLs: OR 0.36, 95% CI 0.19-0.71; for DWMLs: OR 0.35, 95% CI 0.20-0.63) and apoA-1 (for PVWMLs: OR 0.27, 95% CI 0.11-0.66; for DWMLs: OR 0.22, 95% CI 0.10-0.48) were inversely associated with the severity of PVWMLs and DWMLs in women but not in men after adjustment for age, hypertension, diabetes, current smoking, daily drinking, body mass index and uric acid.
|
29162363 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Taken together, glycation modifications impair the apoA-I protein functionality in lipid and glucose metabolism, which is expected to have implications for diabetes patients with poorly controlled blood glucose.
|
29802959 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Apolipoprotein A-I exchange is impaired in metabolic syndrome patients asymptomatic for diabetes and cardiovascular disease.
|
28767713 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
The HAE-apoA-I ratio, reflecting the HDL function per concentration unit apoA-I, was significantly lower in the diabetes group both at baseline, 0.33 (SD = 0.06) versus 0.36 (SD = 0.06) %HAE/mg/dL, p < 0.001 and at follow-up, 0.34 (SD = 0.06) versus 0.36 (SD = 0.06) %HAE/mg/dL, p = 0.003.
|
28683835 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Further studies are required in order to explore the possible role of Apo A-V in TG metabolism in diabetes.
|
28848612 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
To identify candidate mechanisms of ApoA-I truncation, we investigated potentially involved enzymes by in silico data mining, and tested the most probable molecule in an established animal model of diabetes.
|
26168996 |
2015 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Apolipoprotein A-I positively associated with diabetes in women independently of apolipoprotein E genotype and apolipoprotein B levels.
|
20116212 |
2010 |
|
Diabetes
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Transcriptional control of apolipoprotein A-I gene expression in diabetes.
|
14988232 |
2004 |
|
Diabetes
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The presence of CAD was associated with current, past or passive smoking, a history of diabetes and high blood pressure, a positive family risk factors in this study; levels were below history of CAD, body fat percentage, waist-hip ratio (WHR), low apolipoprotein A1 or low HDL, lipoprotein (a), glucose, insulin, insulin resistance, C-reactive protein (CRP), total cholesterol to HDL ratio (TC/HDL) and creatinine on univariate conditional logistic regression analysis.
|
14741073 |
2004 |
|
Diabetes
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Total cholesterol, LDL cholesterol, apoB, HDL cholesterol, and apoA1 were significantly higher in children with diabetes.
|
12716788 |
2003 |