APOA1, apolipoprotein A1, 335

N. diseases: 416; N. variants: 32
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.240 Biomarker disease BEFREE Decreased apolipoprotein A-I (apoA-I) and high-density lipoprotein cholesterol (HDL-C) are common in inflammation and sepsis. 29339066 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.240 Biomarker disease BEFREE HDL has anti-inflammatory properties, and the use of Apo A-I mimetic peptides is associated with renal function improvement in animal models of sepsis. 28317295 2017
CUI: C0243026
Disease: Sepsis
Sepsis 		0.240 AlteredExpression disease BEFREE The liver mRNA levels of apoM and apoA1 decreased strongly upon sepsis induction and after 12 hr both were almost completely lost. 26990127 2016
CUI: C0243026
Disease: Sepsis
Sepsis 		0.240 GeneticVariation disease BEFREE We found rs11216153 polymorphism of ApoA1 was associated with ALI, the GG genotype and G allele was common in the ALI patients (76.9%, 88.1%, respectively) than both in the control subjects (55.8%, 75.8%, respectively) and in the sepsis alone patients (58.2%, 78.4%, respectively). 24885977 2014
CUI: C0243026
Disease: Sepsis
Sepsis 		0.240 Therapeutic disease RGD Apolipoprotein A-I mimetic peptide treatment inhibits inflammatory responses and improves survival in septic rats. 19561306 2009