HTR1A, 5-hydroxytryptamine receptor 1A, 3350

N. diseases: 229; N. variants: 9
Disease: Chronic pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0150055
Disease: Chronic pain
Chronic pain 		0.010 AlteredExpression phenotype BEFREE This article targets the 5-HT1A receptors to show that indiscriminate activation of pre and postsynaptic 5-HT1A receptors is likely to produce no therapeutic benefits; biased activation of the 5-HT heteroreceptors may be a useful strategy for treating chronic pain and depression individually as well as in a comorbid condition. 31418663 2019