HTR1B, 5-hydroxytryptamine receptor 1B, 3351

N. diseases: 140; N. variants: 9
Disease: Suicidal ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0438696
Disease: Suicidal
Suicidal 		0.040 GeneticVariation disease BEFREE Association between HTR1B alleles and suicidal ideation in individuals with major depressive disorder. 28007644 2017
CUI: C0438696
Disease: Suicidal
Suicidal 		0.040 GeneticVariation disease BEFREE The rs130058 SNP within the 5-HTR1B gene demonstrated a differential association with increasing suicidal ideation depending on antidepressant type. 21449676 2011
CUI: C0438696
Disease: Suicidal
Suicidal 		0.040 GeneticVariation disease BEFREE A haplotype association study suggested that the rs11568817-rs130058 haplotype of the HTR1B gene is significantly associated with suicidal ideation in MD. 19897250 2009
CUI: C0438696
Disease: Suicidal
Suicidal 		0.040 GeneticVariation disease BEFREE Our findings suggest that 5-HT1B A-161T genetic polymorphism does not play a major role in the susceptibility to MDD, nor is it related to suicidal attempt or the therapeutic response to fluoxetine in MDD. 15365222 2004