HTR1B, 5-hydroxytryptamine receptor 1B, 3351

N. diseases: 140; N. variants: 9
Disease: Mood Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 Biomarker group PSYGENET Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. 20962330 2010
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 Biomarker group PSYGENET Two common genetic polymorphisms of 5-HT(1B) receptors, G861C and C129T, have been implicated in affective disorders. 19702551 2009
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 Biomarker group PSYGENET The 5-HT1B KO mouse may be useful for investigating the altered entrainment evident during this serious mood disorder. 16461982 2006
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 Biomarker group PSYGENET Alterations in 5-HT(1A,) 5-HT(1B), and 5-HT(2A) mRNA levels in the brains of subjects with both mood disorders and schizophrenia add further support for hypothesis of dysregulation of the serotonergic system in these psychiatric disorders. 14744462 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 GeneticVariation group LHGDN Alterations in 5-HT(1A,) 5-HT(1B), and 5-HT(2A) mRNA levels in the brains of subjects with both mood disorders and schizophrenia add further support for hypothesis of dysregulation of the serotonergic system in these psychiatric disorders. 14744462 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 GeneticVariation group BEFREE Alterations in 5-HT(1A,) 5-HT(1B), and 5-HT(2A) mRNA levels in the brains of subjects with both mood disorders and schizophrenia add further support for hypothesis of dysregulation of the serotonergic system in these psychiatric disorders. 14744462 2004