HTR1E, 5-hydroxytryptamine receptor 1E, 3354

N. diseases: 9; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.010 Biomarker disease BEFREE Finally, we find that phosphorylation of Dam1p on S31 is reduced when glucose is limiting as well as during α-factor arrest, conditions that inhibit PKA activity. 30546002 2019
CUI: C1263846
Disease: Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder 		0.010 GeneticVariation disease BEFREE In addition, we also carried on a casecontrol study to explore the relevance between potential candidate genes 5-HTR1A, 5-HTR1E, 5-HTR3A and ADHD. 30074224 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.010 Biomarker group BEFREE S31-201 treatment significantly ameliorated the IL-22 effects of increased blood pressure and endothelial dysfunction. 28974499 2017
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.010 Biomarker phenotype BEFREE S31-201 treatment significantly ameliorated the IL-22 effects of increased blood pressure and endothelial dysfunction. 28974499 2017
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.010 GeneticVariation disease BEFREE Two additional SNPs, rs10051667 (S31) and rs967771 (S32), previously associated with alcohol dependence and bipolar disorder respectively, were also analyzed. 26561861 2015
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.010 GeneticVariation disease BEFREE Two additional SNPs, rs10051667 (S31) and rs967771 (S32), previously associated with alcohol dependence and bipolar disorder respectively, were also analyzed. 26561861 2015
CUI: C1266129
Disease: Atypical Lipoma
Atypical Lipoma 		0.010 Biomarker disease BEFREE Our findings suggest a novel role of CHK1 as an H3.3S31 kinase, and that CHK1-mediated H3.3S31ph plays an important role in the maintenance of chromatin integrity and cell survival in ALT cancer cells. 25690891 2015
CUI: C0017638
Disease: Glioma
Glioma 		0.010 AlteredExpression disease BEFREE In addition, only three glioma cell lines expressed the 5-HT1E receptor. 8883928 1996
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.010 Biomarker disease BEFREE Association of the HLA-A2, CW2, B27, S31, DR2 haplotype with ankylosing spondylitis. A possible role of non-B27 factors in the disease. 8112024 1993