ICAM1, intercellular adhesion molecule 1, 3383

N. diseases: 737; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 Biomarker disease BEFREE The present study aims to assess the diagnostic value of intercellular adhesion molecule-1 (ICAM-1) in individuals with sepsis. 31192950 2019
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 Biomarker disease BEFREE The serum levels of cTnI, BNP, CK-MB, Mb, NF-κB, TLR-4, TNF-α and ICAM-1 in the sepsis model group were higher than those in the control group. 31281454 2019
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 AlteredExpression disease BEFREE Blood from human sepsis patients was examined for VCAM-1 and ICAM-1 and levels were correlated with blood levels of IαI. 31028466 2019
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 AlteredExpression disease BEFREE The present review highlights the role of various miRNAs in controlling the expression of E-selectin, ICAM-1, and VCAM-1: a type of regulation that can be harnessed for therapeutic prevention of inflammation-associated diseases such as atherosclerosis and sepsis. 29565737 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 AlteredExpression disease BEFREE ICAM-1 level in the sepsis and the SIRS groups was significantly higher than that in the control group (P<0.05), and it is also higher in the sepsis group than in the SIRS group. 30542424 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 AlteredExpression disease BEFREE We hypothesize that CIRP induces ICAM-1 expression in neutrophils causing injury to the lungs during sepsis. 29345380 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 AlteredExpression disease BEFREE Tephrosin attenuates sepsis induced acute lung injury in rats by impeding expression of ICAM-1 and MIP-2. 29432911 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 Biomarker disease BEFREE Unbiased hierarchical clustering identified five different clusters of sepsis mediators, including one with markers of platelet activation (e.g., thrombospondin-1) positively associated with platelet count, one with markers of inflammation (e.g., tumor necrosis factor alpha and heat shock protein 70), and endothelial dysfunction (e.g., intercellular adhesion molecule-1 and vascular cell adhesion molecule-1) negatively associated with platelet count, and another involving growth factors of thrombopoiesis (e.g., thrombopoietin), also negatively associated with platelet count. 29028771 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 Biomarker disease RGD Effects of hydroxyethyl starch (130 kD) on brain inflammatory response and outcome during normotensive sepsis. 20451670 2010
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 AlteredExpression disease LHGDN Injury of the blood brain barrier and up-regulation of icam-1 in polymicrobial sepsis. 18164036 2008
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 AlteredExpression disease LHGDN Serum soluble ICAM-1, VCAM-1, L-selectin, and P-selectin levels as markers of infection and their relation to clinical severity in neonatal sepsis. 17564956 2007
CUI: C0243026
Disease: Sepsis
Sepsis
0.300 Biomarker disease BEFREE We propose that ICAM-1(Kilifi) may be associated with reduced rates of tissue damage and of death due to sepsis. 16288410 2005