RAB7B, RAB7B, member RAS oncogene family, 338382

N. diseases: 65; N. variants: 0
Disease: Toxic Shock Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600327
Disease: Toxic Shock Syndrome
Toxic Shock Syndrome 		0.010 Biomarker disease BEFREE <i>Staphylococcus aureus</i> is a pathogen that causes severe infectious diseases that eventually lead to septic and toxic shock.<i>S. aureus</i> infection is characterized by the production of virulence factors, including enzymes and toxins.After internalization <i>S. aureus</i> resides in a phagosome labeled with Rab7 protein.Here, we show that <i>S. aureus</i> generates tubular structures marked with the small GTPases Rab1b and Rab7 and by the autophagic protein LC3 at early times post-infection. 29046869 2017