HCAR2, hydroxycarboxylic acid receptor 2, 338442

N. diseases: 65; N. variants: 2
Disease: Mitral Valve Stenosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026269
Disease: Mitral Valve Stenosis
Mitral Valve Stenosis 		0.010 Biomarker disease BEFREE Although the DMF/MMF mechanism of action remains unclear, evidence suggests that the activation of HCA<sub>2</sub>/GPR109A pathway downregulates the immune response and may activate anti-inflammatory response in the intestinal mucosa, possibly leading to reduction in CNS tissue damage in MS patients. 29763776 2018