IRF8, interferon regulatory factor 8, 3394

N. diseases: 149; N. variants: 20
Disease: Tuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.020 Biomarker disease BEFREE Our data define IRF-8 as an essential factor for the maintenance of proper immune cell recruitment in granulomas and LS required to restrain Mtb infection. 23717393 2013
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.020 GeneticVariation disease BEFREE In the IRF8 gene, interestingly, we found that three tagSNPs (rs925994 and rs11117415 located in the intron region; rs10514611 located in the 3'UTR) were associated with risk of tuberculosis after Bonferroni correction. 22879909 2012