TMEM240, transmembrane protein 240, 339453

N. diseases: 40; N. variants: 8
Disease: Bradykinesia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233565
Disease: Bradykinesia
Bradykinesia 		0.010 Biomarker phenotype BEFREE A systematic review of all previously reported SCA21 patients (n = 42) demonstrates that SCA21 is a relatively early-onset SCA (median onset age 18 years; range 1-61 years) with frequent non-cerebellar involvement, including hyporeflexia (69%), bradykinesia (65%), slow saccades (38%) and pyramidal signs (17%). 30522958 2019