|
Esophageal Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Esophageal cancer-related gene 1 (ECRG1) is a novel tumor suppressor gene known to affect matrix remodeling, cell growth, and differentiation.
|
23869757 |
2013 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Esophageal cancer-related gene 1 (ECRG1) is a novel tumor suppressor gene known to affect matrix remodeling, cell growth, and differentiation.
|
23869757 |
2013 |
|
Esophageal carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Esophageal cancer-related gene 1 (ECRG1) is a novel tumor suppressor gene known to affect matrix remodeling, cell growth, and differentiation.
|
23869757 |
2013 |
|
Squamous cell carcinoma of esophagus
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Meta-analysis of published studies, exploring role of ECRG1 polymorphism in ESCC risk, was carried out using MIX 2.0 software.
|
23869757 |
2013 |
|
Malignant neoplasm of esophagus
|
0.050 |
Biomarker
|
disease |
BEFREE |
Esophageal cancer-related gene 1 (ECRG1) is a novel tumor suppressor gene known to affect matrix remodeling, cell growth, and differentiation.
|
23869757 |
2013 |
|
Esophageal Neoplasms
|
0.050 |
GeneticVariation
|
group |
BEFREE |
So far no evidence regarding the role of the ECRG1 gene in this cancer has been reported from the Kashmir valley, located on the border of the high risk 'esophageal cancer belt'.
|
21517269 |
2011 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
ECRG1 (esophageal cancer related gene 1) is a novel candidate member of the tumor suppressor gene family previously found to be down regulated in human esophageal cancer (ESCC).
|
21517269 |
2011 |
|
Esophageal carcinoma
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
So far no evidence regarding the role of the ECRG1 gene in this cancer has been reported from the Kashmir valley, located on the border of the high risk 'esophageal cancer belt'.
|
21517269 |
2011 |
|
Squamous cell carcinoma of esophagus
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
A statistically significantly increased risk of ESCC was found to be associated with the ECRG1 Arg/Gln and Gln/Gln genotype occurrence compared to the Arg/Arg genotype (odds ratio (OR) 1.698, 95% confidence interval (CI) 1.112-2.593); P= 0.0138) was observed.
|
21517269 |
2011 |
|
Malignant neoplasm of esophagus
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
So far no evidence regarding the role of the ECRG1 gene in this cancer has been reported from the Kashmir valley, located on the border of the high risk 'esophageal cancer belt'.
|
21517269 |
2011 |
|
Esophageal Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Esophageal-cancer-related gene1 (ECRG1) short tandem repeats are associated with higher risk for developing esophageal squamous cell carcinoma.
|
19052822 |
2009 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
This study examined SNPs in ECRG1 in a similar tumor type (oral squamous cell carcinoma; OSCC) and investigated the relationship between SNPs in ECRG1 and the clinical outcome of patients with OSCC.
|
19394797 |
2009 |
|
Esophageal carcinoma
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
The aim of the present study was to evaluate the impact of DNA polymorphisms in the coding region of ECRG1 in esophageal carcinoma.
|
19052822 |
2009 |
|
Squamous cell carcinoma of esophagus
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Esophageal-cancer-related gene1 (ECRG1) short tandem repeats are associated with higher risk for developing esophageal squamous cell carcinoma.
|
19052822 |
2009 |
|
Squamous cell carcinoma of esophagus
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
A single nucleotide polymorphism (SNP) (Arg290Gln) found in the coding region of ECRG1 might play a role in susceptibility to esophageal squamous cell carcinoma.
|
19394797 |
2009 |
|
Malignant neoplasm of esophagus
|
0.050 |
Biomarker
|
disease |
BEFREE |
Esophageal-cancer-related gene1 (ECRG1) short tandem repeats are associated with higher risk for developing esophageal squamous cell carcinoma.
|
19052822 |
2009 |
|
Esophageal Neoplasms
|
0.050 |
AlteredExpression
|
group |
LHGDN |
Since ECRG-1 gene significantly suppresses the growth of NEC cells both in vitro and in vivo, its loss may contribute to the causation and progression of the EC in Lin-xian county, which is a high incidence area of EC in China.
|
17971341 |
2008 |
|
Esophageal Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Since ECRG-1 gene significantly suppresses the growth of NEC cells both in vitro and in vivo, its loss may contribute to the causation and progression of the EC in Lin-xian county, which is a high incidence area of EC in China.
|
17971341 |
2008 |
|
Neoplasms
|
0.050 |
AlteredExpression
|
group |
BEFREE |
Over-expression of ECRG-1 in NEC cells can also inhibit tumor formation in nude mice.
|
17971341 |
2008 |
|
Esophageal carcinoma
|
0.050 |
Biomarker
|
disease |
BEFREE |
Since ECRG-1 gene significantly suppresses the growth of NEC cells both in vitro and in vivo, its loss may contribute to the causation and progression of the EC in Lin-xian county, which is a high incidence area of EC in China.
|
17971341 |
2008 |
|
Malignant neoplasm of esophagus
|
0.050 |
Biomarker
|
disease |
BEFREE |
Since ECRG-1 gene significantly suppresses the growth of NEC cells both in vitro and in vivo, its loss may contribute to the causation and progression of the EC in Lin-xian county, which is a high incidence area of EC in China.
|
17971341 |
2008 |
|
Esophageal Neoplasms
|
0.050 |
GeneticVariation
|
group |
BEFREE |
Identification of a novel polymorphism Arg290Gln of esophageal cancer related gene 1 (ECRG1) and its related risk to esophageal squamous cell carcinoma.
|
16267096 |
2006 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
We previously cloned and identified the esophageal cancer related gene 1 (ECRG1), a novel candidate tumor suppressor gene, from human esophageal cells.
|
16267096 |
2006 |
|
Esophageal carcinoma
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Identification of a novel polymorphism Arg290Gln of esophageal cancer related gene 1 (ECRG1) and its related risk to esophageal squamous cell carcinoma.
|
16267096 |
2006 |
|
Squamous cell carcinoma of esophagus
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Taken together, our results indicate that the ECRG1 290Gln variant allele might be a genetic susceptibility factor for developing ESCC, especially in the smoking population.
|
16267096 |
2006 |