APOC1, apolipoprotein C1, 341

N. diseases: 95; N. variants: 19
Disease: Dementia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0497327
Disease: Dementia
Dementia 		0.040 GeneticVariation disease BEFREE Genetic variations in apolipoprotein E (APOE) and proximal genes (PVRL2, TOMM40, and APOC1) are associated with cognitive function and dementia, particularly Alzheimer's disease. 29739406 2018
CUI: C0497327
Disease: Dementia
Dementia 		0.040 GeneticVariation disease BEFREE The haplotypes E*3/-317*ins and E*4/-317*ins of APOE/APOC1 genes were significantly more frequent in the groups with Alzheimer's disease and dementia in general (P < 0.001). 21533863 2011
CUI: C0497327
Disease: Dementia
Dementia 		0.040 Biomarker disease BEFREE Previous research has shown that polymorphisms of the apolipoproteins E ( APOE) and APOC1 represent genetic risk factors for dementia and for cognitive impairment in the elderly. 12736801 2003
CUI: C0497327
Disease: Dementia
Dementia 		0.040 GeneticVariation disease BEFREE Apo E and Apo CI loci are associated with dementia in younger but not older late-onset cases. 9681640 1998