IDE, insulin degrading enzyme, 3416

N. diseases: 71; N. variants: 19
Disease: Varicella zoster ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0740380
Disease: Varicella zoster
Varicella zoster 		0.020 Biomarker disease BEFREE We shortly discuss a possible contribution of insulin-degrading enzyme to Alzheimer´s disease pathology by binding varicella zoster virus glycoprotein E, which increases the infectivity and cell-cell spread of the virus. 30806771 2019
CUI: C0740380
Disease: Varicella zoster
Varicella zoster 		0.020 AlteredExpression disease BEFREE Transfection of cell lines impaired for VZV infection with a plasmid expressing human IDE resulted in increased entry and enhanced infection with cell-free and cell-associated virus. 17055432 2006