IDE, insulin degrading enzyme, 3416

N. diseases: 71; N. variants: 19
Disease: Cognitive deterioration ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0854193
Disease: Cognitive deterioration
Cognitive deterioration 		0.010 AlteredExpression disease BEFREE Together, our results indicate that while the absence of RAGE was associated with increased insulin-degrading enzyme activity in the brain, it was not sufficient to prevent or ameliorate cognitive deterioration, Abeta accumulation and microglial activation in the arcAbeta mouse model of AD. 20145420 2009