IDH2, isocitrate dehydrogenase (NADP(+)) 2, 3418

N. diseases: 380; N. variants: 15
Disease: Adult Astrocytic Tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332183
Disease: Adult Astrocytic Tumor
Adult Astrocytic Tumor 		0.020 Biomarker disease BEFREE Notably, IDH gene status has been made the major criterion for classification while the manner of grading has remained unchanged: it is based on histological criteria that arose from studies which antedated knowledge of the importance of IDH status in diffuse astrocytic tumor prognostic assessment. 29687258 2018
CUI: C1332183
Disease: Adult Astrocytic Tumor
Adult Astrocytic Tumor 		0.020 GeneticVariation disease BEFREE We investigated ATRX mRNA expression and its association with IDH1 and IDH2 mutations in 169 adult astrocytic tumors using whole transcriptome sequencing. 24810474 2014