|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The role of macrophage IL-10/innate IFN interplay during virus-induced asthma.
|
25430775 |
2015 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Additionally, individuals with asthma who are infected with HCV and respond to IFN therapy showed a reduction in symptoms and severity of asthma attacks.
|
26026068 |
2015 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma exacerbation pathogenesis.
|
25630941 |
2015 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, defective IFN-λ production by humans with asthma impairs the control of rhinovirus infection.
|
24329419 |
2014 |
|
Asthma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
IFN-α1, IFN-β1 and IFN-γ mRNA levels correlated with the peak Asthma Index (r = 0.58, P < 0.001; r = 0.57, P = 0.001; and r = 0.51, P = 0.004, respectively).
|
24450586 |
2014 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The results indicate that IAV and RSV control and IFN response to these viruses in airway epithelial cells is remarkably similar between subjects with and without asthma.
|
25216987 |
2014 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The roles of NF-κB and IFN regulatory factor-3 (IRF-3) in the poly(I:C)-mediated production of MMPs and the responsiveness to poly(I:C) of normal lung fibroblasts and asthmatic lung fibroblasts were also investigated.
|
24760149 |
2014 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
These findings suggest that IL-13 may be a putative cytokine suppressing IFN-λ production against airway viral infections in asthmatics.
|
21184733 |
2011 |
|
Asthma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Here, we studied IFN-lambda mRNA expression in the airways of stable asthmatics in comparison with healthy subjects and in relation to asthma symptoms, non-invasive parameters of airway inflammation and lung function parameters.
|
18564328 |
2008 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
AM could increase the expression of T-bet mRNA and Thl cytokines such as IFN-Y, and might reverse the Th2 predominant status in asthma patients.
|
17361521 |
2006 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The goal of this study was to identify variation within the IFN gene cluster that influences susceptibility to asthma and atopic phenotypes.
|
16437122 |
2006 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
IFN-gamma and IFN regulatory factor 1 (IRF-1) affect Th1/Th2 cytokine balance, and influence the differentiation of Th2 cells, which influence the development of asthma.
|
16961714 |
2006 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
LHGDN |
Relevance of the selected cytokine release (TNF-alpha, IL-6, IFN-gamma, and IFN-alpha) to the exacerbation of bronchial asthma from airway mycotic infections. Predominant role of TFN-alpha?
|
12530117 |
2002 |