Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.040 GeneticVariation disease BEFREE Involvement of 17β-hydroxysteroid dehydrogenase type gene 1 937 A>G polymorphism in infertility in Polish Caucasian women with endometriosis. 28405865 2017
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.040 Biomarker disease BEFREE In conclusion, DNG exerts comprehensive inhibition of abnormal estrogen production through inhibition of aromatase and HSD17β1, contributing to a therapeutic effect of DNG on endometriosis. 25767055 2015
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.040 Biomarker disease BEFREE Inhibition of type 1 17β-hydroxysteroid dehydrogenase impairs the synthesis of 17β-estradiol in endometriosis lesions. 24187399 2014
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.040 Biomarker disease BEFREE Another abnormality in endometriosis--deficient 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) type 2 expression--impairs the inactivation of estradiol (E2) to estrone (E1). 10652502 2001