Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 AlteredExpression disease BEFREE IFNAR1 expression level is significantly lower in human colorectal carcinoma tissue than in normal colon tissue. 31228946 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 Biomarker disease BEFREE We found that downregulation of the type I interferon receptor chain IFNAR1 occurs in human CRC and mouse models of CRC. 28196594 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 Biomarker disease BEFREE In this issue of Cancer Cell, Katlinski et al. describe tumor-induced degradation of type I interferon receptor IFNAR1 chain as a new immune-evasion mechanism in colorectal cancers. 28196588 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 GeneticVariation disease BEFREE Seven SNPs in IFNA1, IFNA13, IFNA21, IFNK, IFNAR1 and IFNGR1 were associated with CRC risk. 25350395 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 AlteredExpression disease BEFREE IFNAR1 is a predictor for overall survival and mRNA expression is correlated to IRF7, but not TLR9 in colorectal cancer. 25546690 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 AlteredExpression disease BEFREE In conclusion, CLC and IFNAR1 were identified to be overall differentially expressed between early- and late-onset CRC, and are important in the development of early-onset CRC. 21716316 2011