Disease: Chikungunya Fever ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever 		0.010 Biomarker disease BEFREE A key immune mechanism underlying the safety of VSVΔG-CHIKV, VSVΔG-H5N1, and VLV in the adult brain was the type I interferon response; all three viruses were lethal in the brains of adult mice lacking the interferon receptor, suggesting that the viruses can infect and replicate and spread in brain cells if not blocked by interferon-stimulated genes within the brain.<b>IMPORTANCE</b> Vesicular stomatitis virus (VSV) shows considerable promise both as a vaccine vector and as an oncolytic virus. 28077641 2017