IFNG, interferon gamma, 3458

N. diseases: 1519; N. variants: 11
Disease: Biliary Atresia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.060 Biomarker disease BEFREE MicroRNA-29b/142-5p contribute to the pathogenesis of biliary atresia by regulating the IFN-γ gene. 29748604 2018
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.060 AlteredExpression disease BEFREE Hepatic mRNA levels of interferon-gamma or interleukin-4 showed no significant differences between BA and non-BA, while FoxP3 was significantly higher in BA (<i>p</i> = 0.01). 27636194 2017
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.060 AlteredExpression disease BEFREE IFN-γ mRNA expression levels in BA patients were also significantly increased, and the IFN-γ gene promoter region was hypomethylated in BA CD4+ T cells compared with controls and negatively correlated with DNA methylation. 21857377 2011
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.060 GeneticVariation disease BEFREE Polymorphisms of the IFNG gene do not appear to play a major role in the genetic predisposition to BA in Taiwanese children. 19756986 2010
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.060 Biomarker disease BEFREE In the first, we interrogated the hepatic transcriptome of children with biliary atresia and found an interferon-gamma (IFNgamma)-rich proinflammatory footprint at the time of diagnosis. 16819397 2006
CUI: C0005411
Disease: Biliary Atresia
Biliary Atresia 		0.060 Biomarker disease BEFREE These findings were associated with production of interferon gamma in 65% of infants with biliary atresia and no diseased control. 12457789 2002