IGF1, insulin like growth factor 1, 3479

N. diseases: 1206; N. variants: 36
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease BEFREE The aim of this study was to evaluate serum levels of the antineuronal antibodies anti-N-methyl-D-aspartate receptor (NMDAR) and anti-glutamic acid decarboxylase (GAD), and insulin-like growth factor 1 (IGF-1), in patients with bipolar disorder (BD), during manic and depressive episodes and in remission compared to euthymic patients receiving long-term lithium therapy. 30336492 2019
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 GeneticVariation disease BEFREE Bipolar disorder is a recurrent and highly incapacitating illness, related to inflammation and changes in the insulin-like growth factor 1 (IGF-1). 28135645 2017
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease BEFREE Our data support a key role for IGF-1 in lithium resistance/response in the treatment of bipolar disorder. 25740013 2015
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients. 23619527 2013
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease PSYGENET Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder. 21302346 2011
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.340 Biomarker disease BEFREE GWAS data gave good evidence of allelic and haplotypic association between multiple IGF1 SNP's and bipolar disorder (BD). 21302346 2011