IGF1, insulin like growth factor 1, 3479

N. diseases: 1206; N. variants: 36
Disease: Caffeine related disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		0.050 Biomarker group BEFREE The GC-IGF1 axis-mediated testicular dysplasia caused by prenatal caffeine exposure. 31141788 2019
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		0.050 AlteredExpression group BEFREE The topical application of 0.1% caffeine did not induce skin or HF cytotoxicity and stimulated the expression of IGF-1 in the proximal HF ORS. 30746733 2019
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		0.050 AlteredExpression group BEFREE Moreover, in the rat primary adrenal cells, corticosterone (rather than caffeine) was shown to significantly inhibit cell proliferation, IGF1 and PCNA expression, and ERK phosphorylation, which could be reversed by exogenous IGF1. 29343424 2018
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		0.050 Biomarker group BEFREE Prenatal caffeine exprosure increases adult female offspring rat's susceptibility to osteoarthritis via low-functional programming of cartilage IGF-1 with histone acetylation. 29966748 2018
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		0.050 Biomarker group BEFREE The effect of caffeine was dependent on IGF-1-like pathway, although the insulin receptor homolog, <i>daf-2</i> allele, <i>e1371</i>, was dispensable. 30061824 2018