Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
We previously reported that varenicline aggravates atherosclerosis in apolipoprotein E knockout (ApoE KO) mice.
|
31771811 |
2020 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis.
|
31634818 |
2020 |
Atherosclerosis
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Disruption of circadian rhythm by alternating light-dark cycles aggravates atherosclerosis development in APOE*3-Leiden.CETP mice.
|
31599473 |
2020 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
We investigated the effect of such lipid-lowering interventions on atherosclerosis in APOE*3-Leiden.CETP mice, a well-established model for hyperlipidemia.
|
31843957 |
2020 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Subjected to overexpressed GAS5, overexpressed EZH2, or downregulated ABCA1, the Apolipoprotein E (ApoE)<sup>-/-</sup> mice with atherosclerosis showed increased total cholesterol (TC), free cholesterol (FC), cholesterol ester (CE), low-density lipoprotein (LDL) levels, aortic plaque, and lipid accumulation, accompanied by reduced high-density lipoprotein (HDL) level and cholesterol outflow.
|
31830648 |
2020 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Apolipoprotein E knockout (ApoE<sup>-/-</sup> ) mice fed a high-fat-diet (HFD) to establish AS model.
|
31232476 |
2020 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Chronic OSM administration in APOE*3Leiden.CETP mice reduced atherosclerosis development.
|
31461490 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Polydatin attenuates atherosclerosis in apolipoprotein E-deficient mice: Role of reverse cholesterol transport.
|
31085374 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the present study, we demonstrated the role of Plin5 in high-fat-diet-induced atherosclerosis in apolipoprotein E null (ApoE<sup>-/-</sup> ) mice.
|
31297870 |
2019 |
Atherosclerosis
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Among them, 177 proteins were also differentially expressed in diabetic apolipoprotein E deficient (ApoE-/-STZ) mice, suggesting expression changes associated with atherosclerosis independent of the model used.
|
30826357 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Present study was undertaken to determine the pathophysiological significance of sTLT1 in atherosclerosis by employing an observational study on human subjects (n=117) followed by experiments in human macrophages and atherosclerotic apolipoprotein E (apoE)-/- mice.
|
31713591 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Western blot and fluorescence-activated cell sorting analysis showed that Rheb expression was significantly increased in atherosclerotic lesions of atherosclerosis-prone (apoE<sup>-/-</sup> [apolipoprotein E deficient]) mice fed with Western diet.
|
31315433 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Effects of atorvastatin and/or probucol on recovery of atherosclerosis in high-fat-diet-fed apolipoprotein E-deficient mice.
|
30551396 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Mesenchymal stem cells (MSCs) show immunosuppressive activities and alleviate atherosclerosis (AS) formation in apolipoprotein E‑knockout (apoE‑KO) mice.
|
31364743 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
In addition, gypenosides (GP), a KLF14 activator, delayed the development of atherosclerosis in apolipoprotein E deficient (apoE<sup>-/-</sup>) mice.
|
31518965 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
For this purpose, 12-week old hyperlipidemic apolipoprotein E knockout mice were fed a Western-type diet for six weeks to induce both hepatic steatosis and atherosclerosis.
|
30776415 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Overexpression of CTRP9 attenuates the development of atherosclerosis in apolipoprotein E-deficient mice.
|
30426302 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Melatonin Inhibits in Vitro Smooth Muscle Cell Inflammation and Proliferation and Atherosclerosis in Apolipoprotein E-Deficient Mice.
|
30661353 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
44 apolipoprotein E (ApoE)-/- 7 weeks old male rats were randomly divided into normal diet group (NC group) and AS model group (high-fat diet feeding).
|
31002155 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the present study, we used Apolipoprotein E-deficient (ApoE<sup>-/-</sup>) mice model and in vitro cell line of RAW264.7 to explore the mechanisms of ethanol extracts of Danlou tablet (EEDT) in treating atherosclerosis.
|
31181336 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
In conclusion, pre- and postnatal inflammation have additive and deleterious effects on the development of atherosclerosis in ApoE knockout mice.
|
31088858 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
In this study, we collected blood samples from patients of coronary artery diseases and apolipoprotein E (ApoE)<sup>-/-</sup> mice that were fed a Western diet for 12 wk to induce atherosclerosis and found that serum CTRP13 level was decreased.
|
30222079 |
2019 |
Atherosclerosis
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Physical exercise inhibits atherosclerosis development by regulating the expression of neuropeptide Y in apolipoprotein E-deficient mice.
|
31605707 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
The effect of MALAT1 on atherosclerosis was determined in apolipoprotein E-deficient (Apoe<sup>-</sup><sup>/-</sup>) MALAT1-deficient (Malat1<sup>-/-</sup>) mice that were fed with a high-fat diet and by studying the regulation of MALAT1 in human plaques.
|
30586743 |
2019 |
Atherosclerosis
|
0.400 |
Biomarker
|
disease |
BEFREE |
Allergic asthma aggravated atherosclerosis increases cholesterol biosynthesis and foam cell formation in apolipoprotein E-deficient mice.
|
31558320 |
2019 |