APOE, apolipoprotein E, 348

N. diseases: 1049; N. variants: 62
Disease: Prodromal Alzheimer's disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3805054
Disease: Prodromal Alzheimer's disease
Prodromal Alzheimer's disease 		0.050 Biomarker disease BEFREE APOE ɛ4-specific cerebrospinal fluid (CSF) Aβ42/P-tau cut-offs were used to identify aMCI with prodromal AD. 30958351 2019
CUI: C3805054
Disease: Prodromal Alzheimer's disease
Prodromal Alzheimer's disease 		0.050 AlteredExpression disease BEFREE APOE ε4 is associated with higher levels of CSF SNAP-25 in prodromal Alzheimer's disease. 30144541 2018
CUI: C3805054
Disease: Prodromal Alzheimer's disease
Prodromal Alzheimer's disease 		0.050 GeneticVariation disease BEFREE However, this measure was not changed during preclinical or prodromal Alzheimer's disease and was not associated with amyloid positron emission tomography or APOE genotype. 28061383 2017
CUI: C3805054
Disease: Prodromal Alzheimer's disease
Prodromal Alzheimer's disease 		0.050 GeneticVariation disease BEFREE Recent investigations have suggested that APOE polymorphisms do not contribute to non-pathological cognitive function and that any effect is likely due to prodromal Alzheimer's disease (AD). 24946073 2014
CUI: C3805054
Disease: Prodromal Alzheimer's disease
Prodromal Alzheimer's disease 		0.050 GeneticVariation disease BEFREE Compensatory strategies, as reflected by more frequent mnemonics use in APOE4 carriers, may reflect underlying metabolic changes in the brain regions associated with prodromal Alzheimer disease. 16585474 2006