IGF2, insulin like growth factor 2, 3481

N. diseases: 604; N. variants: 19
Disease: Lymphocytic infiltration ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1262091
Disease: Lymphocytic infiltration
Lymphocytic infiltration 		0.010 Biomarker disease BEFREE Treatment of Tg-IGF2 mice with subdiabetogenic doses of streptozotocin or crossing these mice with a transgenic model of islet lymphocytic infiltration promoted the development of overt diabetes, suggesting that IGF2 makes islets more susceptible to β-cell damage and immune attack. 25971976 2015