IGF2, insulin like growth factor 2, 3481

N. diseases: 604; N. variants: 19
Disease: Malignant transformation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 PosttranslationalModification phenotype BEFREE Alteration of oncogenic IGF-II gene methylation status associates with hepatocyte malignant transformation. 30692043 2019
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 AlteredExpression phenotype BEFREE Abnormal expression of insulin-like growth factor II (IGF-II) is associated with the hepatocyte malignant transformation and hepatocellular carcinoma (HCC) progress. 22684773 2012
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 GeneticVariation phenotype BEFREE We studied the activation status of the Wnt and Notch pathways and the differential expression of hepatocyte nuclear factor 4alpha, EGFR, and IGF2 genes, relevant to liver development and malignant transformation in histologic variants of hepatoblastoma. 19200579 2009