Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 AlteredExpression disease BEFREE C/EBPalpha and beta induced an increase in IGFBP-5 transcription in human and murine NB cells similar to that obtained upon RA treatment. 15777798 2005
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 Biomarker disease BEFREE Together, these data demonstrate the importance of IGFBP-5 for NB cell functions and suggest that IGFBP-5 might serve as a novel therapeutic target in NB. 15618969 2005
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 Biomarker disease BEFREE Here, we present evidence that the expression of IGFBP-5 is a common feature of neuroblastoma cell lines and that IGFBP-5 acts in concert with IGF-2 in inducing cell proliferation. 15650232 2004
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 AlteredExpression disease BEFREE Expression of insulin-like growth factor-binding protein 5 in neuroblastoma cells is regulated at the transcriptional level by c-Myb and B-Myb via direct and indirect mechanisms. 11973331 2002