DisGeNET - a database of gene-disease associations

HCN1, hyperpolarization activated cyclic nucleotide gated potassium channel 1, 348980

N. diseases: 157; N. variants: 18

Disease: Tonic - clonic seizures ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0494475
Disease:	Tonic - clonic seizures

Tonic - clonic seizures

0.400

Biomarker

disease

CTD_human

Increased seizure severity and seizure-related death in mice lacking HCN1 channels.

20384728

2010

CUI:	C0494475
Disease:	Tonic - clonic seizures

Tonic - clonic seizures

0.400

Biomarker

disease

HPO